Kappa-opioid receptor binding varies inversely with tumor grade in human gliomas.

Abstract

BACKGROUND Opioid agonists can inhibit cell proliferation in various neural tumor cell lines, including rat gliomas. Because opioid antimitogenic effects are mediated by opioid receptors, it was of interest to the authors to determine opioid receptor levels in human brain tumors. METHODS Specimens obtained at craniotomy from 30 patients with glioma and… (More)

Topics

Cite this paper

@article{Pan1998KappaopioidRB, title={Kappa-opioid receptor binding varies inversely with tumor grade in human gliomas.}, author={Emilie Pan and Laura M. Bohn and Mariana M Belcheva and George E Thomas and Anantha N. Manepalli and James Y. Mamone and F. E. Johnson and Carmine J. Coscia}, journal={Cancer}, year={1998}, volume={83 12}, pages={2561-6} }