Kappa opioid agonist-induced changes in IOP: correlation with 3H-NE release and cAMP accumulation.

@article{Moore2001KappaOA,
  title={Kappa opioid agonist-induced changes in IOP: correlation with 3H-NE release and cAMP accumulation.},
  author={Terri T. Moore and David E. Potter},
  journal={Experimental eye research},
  year={2001},
  volume={73 2},
  pages={167-78}
}
Opioid receptors have been demonstrated to modulate various functions in the eye. This research project was designed to determine and compare the effects of kappa opioid agonists on selected parameters that influence ocular hydrodynamics. Experiments determined the effects of two relatively selective kappa opioid receptor agonists, ICI 204 448 (ICI), which has limited ability to penetrate the blood-brain barrier, and spiradoline mesylate on: (1) in vivo parameters, intraocular pressure (IOP… CONTINUE READING