Kappa Opioids, Salvinorin A and Major Depressive Disorder

  title={Kappa Opioids, Salvinorin A and Major Depressive Disorder},
  author={George Townsend Taylor and Francesca Maria Manzella},
  booktitle={Current neuropharmacology},
Opioids are traditionally associated with pain, analgesia and drug abuse. It is now clear, however, that the opioids are central players in mood. The implications for mood disorders, particularly clinical depression, suggest a paradigm shift from the monoamine neurotransmitters to the opioids either alone or in interaction with monoamine neurons. We have a… CONTINUE READING