Kaposi's sarcoma among persons with AIDS: a sexually transmitted infection?

  title={Kaposi's sarcoma among persons with AIDS: a sexually transmitted infection?},
  author={Valerie Beral and ThomasA. Peterman and Ruth L. Berkelman and Harold W. Jaffe},
  journal={The Lancet},
Is risk of Kaposi's sarcoma in AIDS patients in Britain increased if sexual partners came from United States or Africa?
The data suggest that Kaposi's sarcoma is caused by a sexually transmissible agent which was introduced into the British homosexual population mainly from the United States.
Cell-homologous genes in the Kaposi's sarcoma-associated rhadinovirus human herpesvirus 8: determinants of its pathogenicity?
Based on PCR, the prevalence of HHV-8 appeared to be high in the general population in Uganda, while searches in non-KS tumors and in normal tissues showed that the virus is rarely detectable in Caucasians.
Kaposi's sarcoma.
Human herpesvirus 8 and Kaposi's sarcoma in persons infected with human immunodeficiency virus.
  • J. Gnann, P. Pellett, H. Jaffe
  • Medicine, Biology
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2000
Antiretroviral therapy to control HIV replication and to limit the associated immunodeficiency is currently the best approach for preventing KS in persons infected with HHV-8 and HIV.
Risk Factors for Kaposi's Sarcoma in Patients With Advanced Human Immunodeficiency Virus Disease Treated With Zidovudine
This large cohort study provides further evidence for an association between risk for cytomegalovirus infection and KS, especially among male homosexuals.
Kaposi's sarcoma-associated herpesvirus and sexual transmission of cancer risk.
There is now sufficient evidence to declare Kaposi's sarcoma-associated herpesvirus (KSHV), or human herpesv virus 8, a necessary, albeit not sufficient, cause of KS.
Natural history of HIV infection.
Other ‘high-risk groups’ were also soon recognized, including haemophiliacs, the heterosexual partners of patients with AIDS and children, which does rather suggest that infectivity in donors rises as they develop symptoms.
Seroconversion to antibodies against Kaposi's sarcoma-associated herpesvirus-related latent nuclear antigens before the development of Kaposi's sarcoma.
In most patients with kaposi's sarcoma and AIDS, seroconversion to positivity for antibodies against KSHV-related nuclear antigens occurs before the clinical appearance of Kaposi's Sarcoma.
Kaposi's sarcoma-associated herpesvirus infection and Kaposi's sarcoma in Brazil.
Results show that KSHV is associated with all forms of KS in Brazilian patients, a fact that supports the role of this virus in KS pathogenesis.
The Incidence of Kaposi Sarcoma Among Injection Drug Users With AIDS in the United States
Injection drug use was not associated with an increased risk of AIDS-related Kaposi sarcoma, and data suggest that IDUs’ risk of acquiring HHV-8, through needle sharing or other behaviors related to injection drug use, is low.


The epidemiology of AIDS-related Kaposi's sarcoma in San Francisco.
The proportion of AIDS patients with Kaposi's sarcoma is continuing to decline in San Francisco and that this decline is not an artifact of the AIDS surveillance system.
Incidence of Kaposi's sarcoma and mycosis fungoides in the United States including Puerto Rico, 1973-81.
The KS case rate among never-married men younger than 50 years old, a surrogate index of homosexuality, was found to be markedly elevated in the post-AIDS period, compared with the case rate of a reference disease, mycosis fungoides.
Kaposi's sarcoma in a 6-day-old infant with human immunodeficiency virus.
To the Editor.— Kaposi's sarcoma is a distinctive feature of full-blown acquired immunodeficiency syndrome (AIDS)1that occurs in young men, runs a rapidly progressive course, and spreads
Kaposi's sarcoma in homosexual men. A seroepidemiologic case-control study.
Logistic regression analysis comparing patients with controls showed significant relative risks for Kaposi's sarcoma associated with the number of partners per month in receptive anal-genital intercourse, occasions per month of " fisting ," and cytomegalovirus antibody titers.
Disease Manifestation among Homosexual Men with Acquired Immunodeficiency Syndrome: A Possible Role of Nitrites in Kaposi's Sarcoma
This study suggests that the use of nitrite inhalants may be a cofactor in the development of Kaposi's sarcoma and by identifying other cofactors, investigators may be able to define additional opportunities for prevention of theDevelopment of AIDS.
Acquired immunodeficiency syndrome in African patients.
This syndrome in patients originating in Central Africa is similar to the acquired immunodeficiency syndrome reported in American patients.
Risk factors for human immunodeficiency virus (HIV) infections in homosexual men.
In multivariate analyses, receptive anal intercourse with ejaculation by nonsteady sexual partners, many sexual partners per month, and other indicators of high levels of sexual activity were highly associated with seroconversions, and none of the sexual practices appeared to offer protection against HIV infection.
Epidemiologic characteristics of blood donors with antibody to human immunodeficiency virus
From March 1985 through July 1986, blood donors who were positive for antibody to human immunodeficiency virus (HIV) were evaluated at three major blood centers in the United States. Of 818,629