Kaposi's sarcoma-associated herpesvirus: a new DNA tumor virus.

  title={Kaposi's sarcoma-associated herpesvirus: a new DNA tumor virus.},
  author={Chris H. Boshoff and Yuan - Chia Chang Yeun - Chung Chang Chin - Chen Chang},
  journal={Annual review of medicine},
Kaposi's sarcoma-associated herpesvirus (KSHV) is a newly identified gammaherpesvirus associated with all clinical forms of Kaposi's sarcoma (KS), body-cavity-based, primary effusion lymphomas (PELs), and a subset of Castleman's disease (CD). Sequence analysis of the KSHV genome demonstrates an extensive array of genes with homology to cellular genes involved in cell cycle regulation, cell proliferation, apoptosis, and immune modulation. Functional studies indicate that these genes may modify… CONTINUE READING
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Identification of a spliced gene from Kaposi’s sarcoma–associated herpesvirus encoding a protein with similarities to latent membrane proteins 1 and 2A of Epstein-Barr virus

  • M Glenn, L Rainbow, F Aurad
  • J. Virol
  • 1999
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