Kalimantacin A, B, and C, novel antibiotics produced by Alcaligenes sp. YL-02632S. II. Physico-chemical properties and structure elucidation.

  title={Kalimantacin A, B, and C, novel antibiotics produced by Alcaligenes sp. YL-02632S. II. Physico-chemical properties and structure elucidation.},
  author={Tatsuhiro Tokunaga and Kazuma Kamigiri and Masaya Orita and Tsunehiko Nishikawa and Minoru Shimizu and Hidetoshi Kaniwa},
  journal={The Journal of antibiotics},
  volume={49 2},
Kalimantacin A, B and C are new antibiotics produced by Alcaligenes sp. YL-02632S. Their structures were elucidated to be novel long chain structure compounds containing O-carbamoyl, amide and carboxylic acid moieties based on various 2D NMR experiments and MS analysis. 
Total Synthesis of Kalimantacin A.
The first total synthesis of kalimantacin A is reported, in which three fragments are prepared and then united via Sonogashira and amide couplings, unlocking routes to further kalIMantacins and analogues for structure-activity relationship studies and clinical evaluation.
Biosynthesis of polyketides by trans-AT polyketide synthases.
This review discusses the biosynthesis of natural products that are generated by trans-AT polyketide synthases, a family of catalytically versatile enzymes that represents one of the major group of
Genome Sequence of Alcaligenes sp. Strain HPC1271
ABSTRACT We report a draft genome sequence of Alcaligenes sp. strain HPC1271, which demonstrates antimicrobial activity against multidrug-resistant bacteria. Antibiotic production by Alcaligenes has
Polyketide β-branching: diversity, mechanism and selectivity.
This review covers 2008 to August 2020 and summarises the diversity of β-branch incorporation and the mechanistic details of each catalytic step, extended to discussion of polyketides containing multipleβ-branches and the selectivity exerted by the PKS to ensure β- Branching fidelity.
Characterization of Alcaligenes faecalis strain AD15 indicating biocontrol activity against plant pathogens.
Results indicated that the biocontrol activity of strain AD15 might be attributed to hydroxylamine, a metabolite in the culture medium, and it had the potential for biopesticide application.
Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights.
A comprehensive list of natural products with antimicrobial activity from Gram-negative bacteria, including information on their biosynthetic origin(s) and molecular target(s), where known.
Selecting lipopeptide‐producing, Fusarium‐suppressing Bacillus spp.: Metabolomic and genomic probing of Bacillus velezensis NWUMFkBS10.5
The results of this study indicate that the maize rhizosphere remains a reservoir for microbial strains with unique beneficial properties and the versatile genomic potential of the best Bacillus isolate emphasizes the continued relevance of Bacillus spp.


Kalimantacins A, B and C, novel antibiotics from Alcaligenes sp. YL-02632S. I. Taxonomy, fermentation, isolation and biological properties.
The taxonomy of the producing strain, fermentation, isolation and biological activities of kalimantacins are reported and inhibit the growth of Staphylococcus aureus and S. epidermidis including multiple-drug resistant strains.
Pseudomonic acid. Part 3. Structure of pseudomonic acid B.
Pseudomonic acid B, a minor antibiotic produced by Pseudomonas fluorescens, has been identified as