Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis.

@article{Wu2006KalanchosidesAN,
  title={Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis.},
  author={P L Wu and Yu-Lin Hsu and Tian-Shung Wu and Kenneth F. Bastow and Kuo-Hsiung Lee},
  journal={Organic letters},
  year={2006},
  volume={8 23},
  pages={5207-10}
}
[Structure: see text] Three new compounds, kalanchosides A-C (1-3), as well as five known compounds, were isolated from the aerial parts of Kalanchoe gracilis. The compound structures were determined by spectroscopic methods. All eight isolated compounds showed significant cytotoxic activity against a panel of human tumor cell lines, with potency reaching the nanomolar range. However, only bryophyllin B (8) inhibited HIV replication in H9 lymphocyte cells. 
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