Kai-Xin-San series formulae alleviate depressive-like behaviors on chronic mild stressed mice via regulating neurotrophic factor system on hippocampus

@inproceedings{Zhu2017KaiXinSanSF,
  title={Kai-Xin-San series formulae alleviate depressive-like behaviors on chronic mild stressed mice via regulating neurotrophic factor system on hippocampus},
  author={Yue Zhu and Cheng Chao and Xiuzhu Duan and Xiaoxuan Cheng and Pei Liu and Shu-Lan Su and Jinao Duan and Tina Ting-xia Dong and Karl Wah-keung Tsim},
  booktitle={Scientific Reports},
  year={2017}
}
Kai-xin-san (KXS) is a famous Chinese medicinal formula applied for treating stress-related psychiatric diseases with the symptoms such as depression, forgetfulness and dizziness. In clinic, the composition ratio of KXS is always varied and KXS series formulae are created. Here, we aim to compare the anti-depressive effect of different ratios of KXS and reveal its action mechanism on regulation of neurotrophic factor system. Firstly, daily intra-gastric administration of chemically standardized… CONTINUE READING
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