KSR Plays CRAF-ty

@article{Shi2011KSRPC,
  title={KSR Plays CRAF-ty},
  author={Fumin Shi and Mark A. Lemmon},
  journal={Science},
  year={2011},
  volume={332},
  pages={1043 - 1044}
}
A scaffold protein has enzymatic activity that controls a major cell signaling pathway. Organization of the bewildering array of known cell signaling proteins into coherent networks is facilitated by “scaffold” proteins that guide local information flow by binding multiple signaling molecules (1). Recent studies on one such scaffold protein called kinase suppressor of RAS (KSR), however, blur distinctions between the scaffold and the “scaffolded” by indicating that KSR itself has enzymatic… 
A pickup in pseudokinase activity.
  • A. Dar
  • Biology, Chemistry
    Biochemical Society transactions
  • 2013
TLDR
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