KSHV-encoded viral interferon regulatory factor 4 (vIRF4) interacts with IRF7 and inhibits interferon alpha production.

Abstract

Before an infection can be completely established, the host immediately turns on the innate immune system through activating the interferon (IFN)-mediated antiviral pathway. Kaposi's sarcoma-associated herpesvirus (KSHV) utilizes a unique antagonistic mechanism of type I IFN-mediated host antiviral immunity by incorporating four viral interferon regulatory… (More)
DOI: 10.1016/j.bbrc.2017.03.101

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@article{Hwang2017KSHVencodedVI, title={KSHV-encoded viral interferon regulatory factor 4 (vIRF4) interacts with IRF7 and inhibits interferon alpha production.}, author={Sung-woo Hwang and DongIk Kim and Jae U Jung and H Lee}, journal={Biochemical and biophysical research communications}, year={2017}, volume={486 3}, pages={700-705} }