KSAC, the first defined polyprotein vaccine candidate for visceral leishmaniasis.

@article{Goto2011KSACTF,
  title={KSAC, the first defined polyprotein vaccine candidate for visceral leishmaniasis.},
  author={Yasuyuki Goto and Ajay Bhatia and Vanitha S. Raman and Hong Liang and Raodoh Mohamath and Alessandro F Picone and Silvia E Z Vidal and Thomas S. Vedvick and Randall F. Howard and Steven G Reed},
  journal={Clinical and vaccine immunology : CVI},
  year={2011},
  volume={18 7},
  pages={1118-24}
}
A subunit vaccine using a defined antigen(s) may be one effective solution for controlling leishmaniasis. Because of genetic diversity in target populations, including both dogs and humans, a multiple-antigen vaccine will likely be essential. However, the cost of a vaccine to be used in developing countries must be considered. We describe herein a multiantigen vaccine candidate comprised of antigens known to be protective in animal models, including dogs, and to be recognized by humans immune… CONTINUE READING