KRIT1/cerebral cavernous malformation 1 protein localizes to vascular endothelium, astrocytes, and pyramidal cells of the adult human cerebral cortex.

Abstract

OBJECTIVE Mutations in KRIT1 cause familial cerebral cavernous malformation, an autosomal dominant disorder affecting primarily the central nervous system vasculature. Although recent studies have suggested that Krev-1 interaction trapped 1 (KRIT1) is a microtubule-associated protein that interacts with integrin cytoplasmic domain-associated protein-1alpha… (More)

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@article{GuzelogluKayisli2004KRIT1cerebralCM, title={KRIT1/cerebral cavernous malformation 1 protein localizes to vascular endothelium, astrocytes, and pyramidal cells of the adult human cerebral cortex.}, author={Ozlem Guzeloglu-Kayisli and Nduka M. Amankulor and Jennifer R. Voorhees and Guven Luleci and Richard P. Lifton and Murat Gunel}, journal={Neurosurgery}, year={2004}, volume={54 4}, pages={943-9; discussion 949} }