KRAS-mutation status in relation to colorectal cancer survival: the joint impact of correlated tumour markers

Abstract

Background:Mutations in the Kirsten Ras (KRAS) oncogene are common in colorectal cancer (CRC). The role of KRAS-mutation status as a prognostic factor, however, is unclear. We evaluated the relationship between KRAS-mutation status and CRC survival, considering heterogeneity in this association by tumour and patient characteristics.Methods:The population… (More)
DOI: 10.1038/bjc.2013.118

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