KRAS and BRAF mutation frequencies in a series of Turkish colorectal cancer patients

@inproceedings{Baskin2014KRASAB,
  title={KRAS and BRAF mutation frequencies in a series of Turkish colorectal cancer patients},
  author={Yasemin Baskin and Gizem Çalibaşi and Arsalan Amirfallah and Yusuf Kagan Dagdeviren and Aras Emre Canda and Sulen Sarioglu and Ozgul Sağol and H{\"u}lya Ellidokuz and Ilhan Oztop and Uğur Yilmaz},
  year={2014}
}
The prognostic value of KRAS and BRAF mutation in colorectal cancer (CRC) is very consistent. Several studies have demonstrated an association between these gene mutations and resistance to anti-EGFR based therapies. Wild type KRAS and BRAF is required for a response to CRC therapy. The aim of this study is to identify the frequency of KRAS and BRAF gene mutations in a series of Turkish CRC patients and to evaluate the relationship between the mutations and demographic features in the Turkish… CONTINUE READING

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