KRAS and BRAF mutation analysis from liquid-based cytology brushings of colorectal carcinoma in comparison with formalin-fixed, paraffin-embedded tissue.

@article{Spathis2010KRASAB,
  title={KRAS and BRAF mutation analysis from liquid-based cytology brushings of colorectal carcinoma in comparison with formalin-fixed, paraffin-embedded tissue.},
  author={Aris T Spathis and John Georgoulakis and Periklis G. Foukas and Maria Kefala and Konstantinos Leventakos and Anastasios N. Machairas and Ioannis J Panayiotides and Petros Karakitsos},
  journal={Anticancer research},
  year={2010},
  volume={30 6},
  pages={1969-75}
}
Real-time PCR-based molecular diagnostic techniques were used for the comparative identification of the most common KRAS and BRAF mutations from methanol liquid-based cytology samples and matched, formalin-fixed and paraffin-embedded tissue samples. Methanol-based fixation and preservation of brushing samples of colorectal carcinomas could contribute to… CONTINUE READING