KRAS Mutation Detection in Paired Frozen and Formalin-Fixed Paraffin-Embedded (FFPE) Colorectal Cancer Tissues

Abstract

KRAS mutation has been unambiguously identified as a marker of resistance to cetuximab-based treatment in metastatic colorectal cancer (mCRC) patients. However, most studies of KRAS mutation analysis have been performed using homogenously archived CRC specimens, and studies that compare freshly frozen specimens and formalin-fixed paraffin-embedded (FFPE… (More)
DOI: 10.3390/ijms12053191

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@inproceedings{Solassol2011KRASMD, title={KRAS Mutation Detection in Paired Frozen and Formalin-Fixed Paraffin-Embedded (FFPE) Colorectal Cancer Tissues}, author={J{\'e}r{\^o}me Solassol and J. Sousa Ramos and Evelyne Crapez and Majda Saifi and Alain Mang{\'e} and Evelyne Vian{\`e}s and P. J. Lamy and Val{\'e}rie Costes and Thierry Maudelonde}, booktitle={International journal of molecular sciences}, year={2011} }