KOPS: DNA motifs that control E. coli chromosome segregation by orienting the FtsK translocase.

@article{Bigot2005KOPSDM,
  title={KOPS: DNA motifs that control E. coli chromosome segregation by orienting the FtsK translocase.},
  author={Sarah Bigot and Omar A Saleh and Christian Lesterlin and Carine Pag{\`e}s and Meriem El Karoui and Cynthia Dennis and Mikhail Grigoriev and J Allemand and François-Xavier Barre and Francois H. Cornet},
  journal={The EMBO journal},
  year={2005},
  volume={24 21},
  pages={3770-80}
}
Bacterial chromosomes are organized in replichores of opposite sequence polarity. This conserved feature suggests a role in chromosome dynamics. Indeed, sequence polarity controls resolution of chromosome dimers in Escherichia coli. Chromosome dimers form by homologous recombination between sister chromosomes. They are resolved by the combined action of two tyrosine recombinases, XerC and XerD, acting at a specific chromosomal site, dif, and a DNA translocase, FtsK, which is anchored at the… CONTINUE READING

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