KLF4 promotes the expression, translocation, and releas eof HMGB1 in RAW264.7 macrophages in response to LPS.

@article{Liu2008KLF4PT,
  title={KLF4 promotes the expression, translocation, and releas eof HMGB1 in RAW264.7 macrophages in response to LPS.},
  author={Junwen Liu and Ying Liu and Huali Zhang and Guangwen Chen and Kangkai Wang and Xian-Zhong Xiao},
  journal={Shock},
  year={2008},
  volume={30 3},
  pages={260-6}
}
Krüppel-like factor 4 (KLF4) is an evolutionarily conserved zinc finger-containing transcription factor with diverse regulatory functions in cell growth, proliferation, differentiation, and embryogenesis. In our previous study, we found that KLF4 mRNA was up-regulated more than 10-fold in adult mice lung tissues after endotoxin stimuli, and that KLF4 can regulate the expression of IL -10, an early inflammatory mediator. To determine whether KLF4 influences the expression and release of high… CONTINUE READING
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