KLF4 deletion alters gastric cell lineage and induces MUC2 expression

Abstract

Gastric cancer is one of the most common types of cancer in the world, particularly in underdeveloped countries. The mechanism of gastric cancer is less understood compared with other types of gastrointestinal (GI) cancers. Krüppel-like factor 4 (KLF4) is a zinc-finger transcription factor and is a potential tumor suppressor in GI cancers. In this study, we… (More)
DOI: 10.1038/cddis.2016.158

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