KLF2 and KLF4 control endothelial identity and vascular integrity.

@article{Sangwung2017KLF2AK,
  title={KLF2 and KLF4 control endothelial identity and vascular integrity.},
  author={Panjamaporn Sangwung and Guangjin Zhou and Lalitha V. Nayak and Ernest R. Chan and Sandeep Kumar and Dong-Won Kang and Rongli Zhang and Xudong Liao and Yuan Lu and Keiki Sugi and Hisashi Fujioka and Hong Xia Shi and Stephanie D Lapping and Chandra C. Ghosh and Sarah J. Higgins and Samir M. Parikh and Hanjoong Jo and Mukesh K Jain},
  journal={JCI insight},
  year={2017},
  volume={2 4},
  pages={e91700}
}
Maintenance of vascular integrity in the adult animal is needed for survival, and it is critically dependent on the endothelial lining, which controls barrier function, blood fluidity, and flow dynamics. However, nodal regulators that coordinate endothelial identity and function in the adult animal remain poorly characterized. Here, we show that endothelial… CONTINUE READING

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