KISS1 Suppresses Apoptosis and Stimulates the Synthesis of E2 in Porcine Ovarian Granulosa Cells

@inproceedings{Xin2019KISS1SA,
  title={KISS1 Suppresses Apoptosis and Stimulates the Synthesis of E2 in Porcine Ovarian Granulosa Cells},
  author={Xiaoping Xin and ZhongHui Li and Yuyi Zhong and Qingqing Li and Jiaying Wang and Hao Zhang and Xiaolong Yuan and Jiaqi Li and Zhengguang Zhang},
  booktitle={Animals : an open access journal from MDPI},
  year={2019}
}
Previous studies have strongly recommended that KISS-1 metastasis suppressor (KISS1) plays an essential gatekeeper of the initiation of reproductive maturation in mammals. However, KISS1 has been recently reported to highly express in ovarian granulosa cells (GCs). But the biological functionalities of KISS1 on cell apoptosis, cell cycle, and synthesis of estradiol-17β (E2) have not been explored in GCs. In this study, using porcine GCs as a cellular model, the overexpression plasmid of KISS1… CONTINUE READING

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