KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly.

@article{Akao2012KIF6LT,
  title={KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly.},
  author={Hironobu Akao and Eliana Y Polisecki and Kouji Kajinami and Stella Trompet and Michele Robertson and Ian Ford and J Wouter Jukema and Anton J. M. de Craen and Rudi G. J. Westendorp and James S. Shepherd and Christopher J. Packard and Brendan M. Buckley and Ernst J. Schaefer},
  journal={Atherosclerosis},
  year={2012},
  volume={220 2},
  pages={456-62}
}
Single nucleotide polymorphisms (SNPs) at the KIF6 (kinesin like protein 6, rs20455 or 719Arg), LPA (lipoprotein(a), rs3798220), TAS2R50 (taste receptor type 2, member 50, rs1376251) and VAMP8 (vesicle-associated membrane protein 8, rs1010) have previously been associated with low density lipoprotein cholesterol (LDL-C) lowering response to statins, coronary heart disease (CHD) at baseline, or CHD events on trial. We examined SNPs at the KIF6 (rs20455 or 719Arg), LPA (rs3798220), TAS2R50… CONTINUE READING

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