KGF induces lipogenesis in alveolar type II cells through a SREBP-1c dependent pathway


Keratinocyte growth factor (KGF) stimulates fatty acid and phospholipid synthesis in alveolar type II cells in vitro. KGF stimulates lipogenic enzymes including fatty acid synthase and stearoyl-CoA desaturase-1 and transcription factors involved in lipogenesis such as SREBP-1c and C/EBPα and C/EBPδ. To define the role of SREBP-1c on the induction of… (More)


1 Figure or Table