• Corpus ID: 38019906

KEY FACTS Noninfectious Prostatic Diseases in Dogs

  title={KEY FACTS Noninfectious Prostatic Diseases in Dogs},
  author={Cristina Gobello and Yanina A Corrada},
The prostate—the only accessory gland of the genital tract in dogs—is under androgenic control. Common canine prostatic disorders include benign prostatic hyperplasia (BPH), prostatitis, cysts, and adenocarcinoma. BPH is a common age-related condition that occurs in 95% of male dogs by 9 years of age. The exact pathogenesis of canine BPH is not completely understood, although it is known that dihydrotestosterone is the key factor in stimulating prostate growth. Clinical signs of BPH include… 
RETRACTED ARTICLE: Diagnostic investigations of canine prostatitis incidence together with benign prostate hyperplasia, prostate malignancies, and biochemical recurrence in high-risk prostate cancer as a model for human study
Chronic prostatic inflammation could be a central mechanism in BPH progression, but the pathological features of tissue inflammation were different between BPH and prostate cancer (PCa).
Surgical management of common canine prostatic conditions.
In intact dogs that present with these disorders, castration should always be part of the specific surgical treatment because it enhances treatment success and may prevent recurrence.
Canine prostatic disease: a review of anatomy, pathology, diagnosis, and treatment.
Emphasis is placed on proper diagnostic sampling of the prostate gland, its fluid, and interpretation of findings, as well as emerging medical options for treatment of canine prostatic disease.
Validation of a model to develop a symptom index for benign prostatic hyperplasia in dogs.
A BPH symptom index was created for the first time in dogs, which may be useful to standardize BPH severity with an objective score and to evaluate the necessity, the kind and the effectiveness of treatment.
The effects of osaterone acetate on clinical signs and prostate volume in dogs with benign prostatic hyperplasia.
In conclusion, OSA quickly reduced clinical signs and volume of the prostate glands in dogs with BPH.
Analysis of lower urinary tract disease of dogs
Dogs from 3 months to 18 years with a median of 8 years were affected, and the most affected breeds were Poodle, Labrador, German shepherd, Schnauzer, Cocker Spaniel and Chihuahua.
Transarterial prostatic embolization: initial experience in a canine model.
The findings suggest transarterial prostatic embolization is a safe procedure that can induce prostatic infarction and ablate the prostate and has potential clinical applications in the care of patients with benign prostatic hyperplasia.
Canine prostate specific esterase (CPSE) as an useful biomarker in preventive screening programme of canine prostate: CPSE threshold value assessment and its correlation with ultrasonographic prostatic abnormalities in asymptomatic dogs
It is suggested that CPSE serum concentration higher than 50 ng/ml in asymptomatic dogs is associated with ultrasonographic alterations and increased the prostatic size (volume by 1.5 times greater than the normal size).
Hormones concentration in the blood of dogs with implant of the Suprelorin 4.7 mg
There was a significant decrease in testosterone levels in the experimental group, as well as an increase in the level of estradiol, luteinizing hormone, thyroid stimulating hormone, and T3 total in blood serum of dogs in experimental groups, which was introduced implant.
Two cases of paraprostatic cysts in castrated male dogs.
These are the first documented cases of paraprostatic cysts that developed after castration in male dogs and should be considered in the differential diagnoses for castrated male dogs with prostatic disease.


Prostatic disorders in the dog.
Recent reports of prostatic intraepithelial neoplasia (PIN) in a high percentage of older male dogs, with and without prostatic adenocarcinoma, suggests that PIN may be a precursor to adenOCarcinomas in the dog as it is believed to be in man.
Clinical and experimental studies of benign prostatic hyperplasia.
The canine prostate appears to be a suitable model for investigating many aspects of abnormal prostate growth related to BPH and it is believed that steroid imprinting in the neonatal and prepubertal period may be of great importance in determining the ultimate growth of the prostate.
The influence of castration on the development of prostatic carcinoma in the dog. 43 cases (1978-1985).
In this study, castration at any age showed no sparing effect on the risk of development of PC in the dog, and work in humans suggests that the adrenal and pituitary glands play a significant role in the disease.
Testicular androgen and estrogen secretion and benign prostatic hyperplasia in the beagle.
The results of the present study are the first to compare Leydig cell structure and steroidogenic function in dogs with BPH with those in age-matched controls and support the concept that the early phase of BPH (glandular hyperplasia) is not related temporally to some defect in the Leydigs cell.
Serum and seminal markers in the diagnosis of disorders of the genital tract of the dog: a mini-review.
Alkaline phosphatase, carnitine and canine prostate-specific arginine esterase seem to be a promising diagnostic tool in nonneoplasic canine prostatic disorders and future studies should also address the quantitative relationship among serum and prostatic androgen levels, prostatics androgen-dependent problems and how these are affected by anti-androgen treatment.
Study of prostatic disease in dogs: 177 cases (1981-1986).
The most common prostatic disease identified in this study was bacterial prostatitis, followed by prostatic cyst, prostatic adenocarcinoma, and benign hyperplasia, and the most common prostrate cancer identified in neutered dogs was prostaticAdenocARCinoma.
Spontaneous benign prostatic hyperplasia in the beagle. Age-associated changes in serum hormone levels, and the morphology and secretory function of the canine prostate.
The growth and functional changes that are associated with the development of BPH and are initiated very early in life reflect an altered sensitivity of the prostate to serum androgens or a response to the relative decrease in the serum androgen to estrogen ratio.
Canine prostatic disease--comparison of radiographic appearance with morphologic and microbiologic findings: 30 cases (1981-1985).
A retrospective analysis was made of radiographs from 24 clinically normal young adult male Beagles used in previously reported base-line research on the distal male urinary tract, finding the largest acceptable prostatic dimension was 70% of the public-promontory distance.
Prostatic intraepithelial neoplasia in dogs with spontaneous prostate cancer
The results are similar to those reported for human PIN and prostate cancer, and indicate that PIN is part of a morphologic continuum in the progression of prostate cancer.
Models for studying benign prostatic hyperplasia
The hormonal-induced canine BPH model is a good alternative that closely resembles human BPH in many aspects and can be used for studying BPH.