• Corpus ID: 54064933


  author={Imaobong Inyang Udousoro and Udeme John Dickson},
Ketogenic diet, a high fat, low carbohydrate diet was devised in 1921 to mimic the effects of starvation originally determined to be beneficial for epileptic seizures. The diet fell out of favour with the development of anticonvulsant agents, but has experienced resurgence in use over the past 20 years, particularly in the treatment of refractory children epilepsy. Since the rebirth of ketogenic diet in the United States of America in the mid-1990s, there has been growing global acceptance of… 

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The ketogenic diet in children with epilepsy

This paper is a review of previous and current papers regarding the proposed mechanisms of the ketogenic diet’s action, and the efficacy of the regimen on epileptic children.

Efficacy of dietary treatments for epilepsy.

  • E. NealJ. Cross
  • Medicine
    Journal of human nutrition and dietetics : the official journal of the British Dietetic Association
  • 2010
A recent randomised controlled trial has shown a significant benefit of the KD compared to no change in treatment, and the use of these dietary therapies in the UK is supported by literature evidence, although often is limited by a lack of resources.

[Ketogenic diet for intractable childhood epilepsy; as an early option as well as a last resort].

  • S. ItoH. Oguni
  • Medicine
    Brain and nerve = Shinkei kenkyu no shinpo
  • 2011
The history, efficacy, side effects, and possible mechanisms underlying theketogenic diet, as well as the experience with the ketogenic diet at Tokyo Women's Medical University are reviewed.

[Ketogenic regime as anti-epileptic treatment: its use in 29 epileptic children].

The ketogenic diet should be considered as an alternative therapy for children with refractory epilepsy, and should be continued during one or 2 years when it is effective.

Plasma lipids in epileptic children treated with the high fat diet.

  • A. Dekaban
  • Medicine, Psychology
    Archives of neurology
  • 1966
It is conceded that children under 8 years of age who suffer predominantly from minor attacks show the best results in the ketogenic diet, but generally attributed to the fact that dietary ketosis is difficult to accomplish in older children and in adults.

Dietary treatment of epilepsy: rebirth of an ancient treatment.

The efficacy of the ketogenic diet-1998: a prospective evaluation of intervention in 150 children.

The ketogenic diet should be considered as alternative therapy for children with difficult-to-control seizures and is more effective than many of the new anticonvulsant medications and is well tolerated by children and families when it is effective.

Medium‐chain triglycerides as a therapy for intractable childhood epilepsy

A diet containing sufficient MCT to induce ketonuria was devised and its effects have been tested in a group of children and adolescents with intractable seizures.

Ketogenic diet and other dietary treatments for epilepsy.

The randomised controlled trials discussed in this review show promising results for the use of KDs in epilepsy, however, the limited number of studies, small sample sizes and a sole paediatric population resulted in a poor overall quality of evidence.

The Use of Ketogenic Diet in Pediatric Patients with Epilepsy

Patients on ketogenic diets who exceed their daily carbohydrate limit have the risk of seizure relapse, necessitating hospital readmission to repeat the diet initiation process, and are at a high risk for diversion from the diet.