KDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage

Abstract

The p53 tumor suppressor protein plays a critical role in orchestrating the genomic response to various stress signals by acting as a master transcriptional regulator. Differential gene activity is controlled by transcription factors but also dependent on the underlying chromatin structure, especially on covalent histone modifications. After screening… (More)
DOI: 10.1093/nar/gkw1281

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Cite this paper

@inproceedings{Castellini2017KDM4BJMJD2BIA, title={KDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage}, author={Laura Castellini and Eui Jung Moon and Olga V. Razorenova and Adam J. Krieg and Rie von Eyben and Amato J. Giaccia}, booktitle={Nucleic acids research}, year={2017} }