Modulation of human Kv4.3/KChIP2 channel inactivation kinetics by cytoplasmic Ca2+
- Christiane Groen, Robert Bähring
- Pflügers Archiv - European Journal of Physiology
- 2017
1 Excerpt
Abstract
Arrhythmogenesis from aberrant electrical remodeling is a primary cause of death among patients with heart disease. Amongst a multitude of remodeling events, reduced expression of the ion channel subunit KChIP2 is consistently observed in numerous cardiac pathologies. However, it remains unknown if KChIP2 loss is merely a symptom or involved in disease… (More)