KCNQ1 and KCNH2 mutations associated with long QT syndrome in a Chinese population.

@article{Liu2002KCNQ1AK,
  title={KCNQ1 and KCNH2 mutations associated with long QT syndrome in a Chinese population.},
  author={Wenling Liu and Junguo Yang and Da-yi Hu and Cailian Kang and Cui-Lan Li and Shuoyan Zhang and Ping Li and Zhijian Chen and Xuguang Qin and K. K. Ying and Yuntian Li and Yushu Li and Zhi-Ming Li and Xin Cheng and Lei Li and Yu Qi and Shenghan Chen and Qing Wang},
  journal={Human mutation},
  year={2002},
  volume={20 6},
  pages={475-6}
}
The long QT syndrome (LQTS) is a cardiac disorder characterized by prolongation of the QT interval on electrocardiograms (ECGs), syncope and sudden death caused by a specific ventricular tachyarrhythmia known as torsade de pointes. LQTS is caused by mutations in ion channel genes including the cardiac sodium channel gene SCN5A, and potassium channel subunit genes KCNQ1, KCNH2, KCNE1, and KCNE2. Little information is available about LQTS mutations in the Chinese population. In this study, we… CONTINUE READING