KCC3-dependent chloride extrusion in adult sensory neurons.

  title={KCC3-dependent chloride extrusion in adult sensory neurons.},
  author={Olivier Lucas and C{\'e}cile Hilaire and Eric Delpire and Fr{\'e}d{\'e}rique Scamps},
  journal={Molecular and cellular neurosciences},
  volume={50 3-4},
The cation-Cl(-) cotransporters participate to neuronal Cl(-) balance and are responsible for the post-natal Cl(-) switch in central neurons. In the adult peripheral nervous system, it is not well established whether a Cl(-) transition occurs during maturation. We investigated the contribution of cation-Cl(-) cotransporters in the Cl(-) handling of sensory neurons derived from the dorsal root ganglia (DRG) of neonatal mice (postnatal days 1-6) and adult mice. Gramicidin-perforated patch-clamp… CONTINUE READING
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