KAP1 Is Associated With Peritoneal Carcinomatosis in Gastric Cancer

  title={KAP1 Is Associated With Peritoneal Carcinomatosis in Gastric Cancer},
  author={PhD Takeshi Yokoe and PhD Yuji Toiyama and Yoshinaga Okugawa and PhD Koji Tanaka and PhD Masaki Ohi and PhD Yasuhiro Inoue and PhD Yasuhiko Mohri and PhD Chikao Miki and PhD Masato Kusunoki},
  journal={Annals of Surgical Oncology},
KRAB-associated protein 1 (KAP1) is a universal corepressor for Kruppel-associated box zinc finger proteins. Here we demonstrate the biological function and clinical significance of KAP1 expression in gastric cancer. Knockdown of the KAP1 gene by siRNA transfection was performed to evaluate KAP1 function in gastric cancer cells. Real-time polymerase chain reaction was performed in 91 samples obtained from gastric cancer patients. The proliferation rate was impaired and resistance to anoikis was… CONTINUE READING
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