K99 surface haemagglutinin of enterotoxigenic E. coli recognize terminal N-acetylgalactosamine and sialic acid residues of glycophorin and other complex glycoconjugates.

Abstract

The possible nature of the erythrocyte receptor for K99 haemagglutinin is described. The receptor is a glycophorin which possesses NANA alpha 2-6 GalNAc structures for which this haemagglutinin has a strong affinity. Human, porcine and equine erythrocytes which are haemagglutinated by K99 all have similar glycophorin oligosaccharide structures. K99 has… (More)

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