K-ras oncogene subtype mutations are associated with survival but not expression of p53, p16(INK4A), p21(WAF-1), cyclin D1, erbB-2 and erbB-3 in resected pancreatic ductal adenocarcinoma.

@article{Kawesha2000KrasOS,
  title={K-ras oncogene subtype mutations are associated with survival but not expression of p53, p16(INK4A), p21(WAF-1), cyclin D1, erbB-2 and erbB-3 in resected pancreatic ductal adenocarcinoma.},
  author={Anthony Kawesha and Payla Ghaneh and A Andr{\'e}n-sandberg and D Ograed and Robert Skar and Sigmund Dawiskiba and James D Evans and Fiona Campbell and Nick R. Lemoine and John P Neoptolemos},
  journal={International journal of cancer},
  year={2000},
  volume={89 6},
  pages={469-74}
}
Previous studies of molecular prognostic markers following resection for exocrine pancreatic cancer have produced conflicting results. Our aim was to undertake a comprehensive analysis of potentially useful molecular markers in a large, multicentre patient population and to compare these markers with standard pathological prognostic variables. Formalin-fixed, paraffin-embedded specimens of pancreatic ductal adenocarcinoma were analysed from 157 patients [100 men and 57 women with a median… CONTINUE READING
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