• Medicine
  • Published 2000

K-ras AND p53 GENE MUTATION IN PORTAL VEIN BLOOD AND ITS RELATIONSHIP WITH HEPATIC METASTASIS FROM LARGE INTESTINE CARCINOMA

@inproceedings{Hong2000KrasAP,
  title={K-ras AND p53 GENE MUTATION IN PORTAL VEIN BLOOD AND ITS RELATIONSHIP WITH HEPATIC METASTASIS FROM LARGE INTESTINE CARCINOMA},
  author={Jiang Hong},
  year={2000}
}
Objective:To explore the relationship between K ras and p53 gene mutation in portal vein blood and hepatic metastasis from large intestine carcinoma.Methods: By PCR SSCP and PCR RFLP, K ras and p53 gene mutation in carcinoma tissues,protal vein blood and peripheral blood from large intestine carcinoma patients were studied,and a two year post operation follow up of hepatic metastasis was made.Results:K ras gene mutation in portal vein blood were founded in 6 of 30 cases,hepatic metastasis rates… CONTINUE READING

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