K-Shrec Analysis of Kinetochore Protein Archetecture at Nm Scale Accuracy

@inproceedings{Salmon2011KShrecAO,
  title={K-Shrec Analysis of Kinetochore Protein Archetecture at Nm Scale Accuracy},
  author={Edward D. Salmon},
  year={2011}
}
Kinetochores link centromeric DNA to the plus ends of spindle microtubules (MTs). They contain more than 70 different proteins that function in chromatin anchorage, microtubule attachment, the spindle assembly checkpoint (SAC), force generation, and correction of MT attachment errors. Protein architecture within the kinetochore is poorly understood because the kinetochore core is only about 100 nm thick and it is has been very difficult to obtain molecular specificity at the resolution of… CONTINUE READING