K-RAS Mutations in Ovarian and Extraovarian Lesions of Serous Tumors of Borderline Malignancy

Abstract

K-RAS mutations are the most frequent molecular genetic alteration in serous ovarian tumors of borderline malignancy (SBOT). The pathogenesis of associated contralateral tumors and extraovarian implants and Müllerian inclusion cysts is obscure. We hypothesized that the comparison of K-RAS mutations in these lesions might help to distinguish multifocal from… (More)
DOI: 10.1097/01.LAB.0000056994.81259.32

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