K-Cl cotransport function and its potential contribution to cardiovascular disease.

@article{Adragna2007KClCF,
  title={K-Cl cotransport function and its potential contribution to cardiovascular disease.},
  author={Norma C. Adragna and Peter K. Lauf},
  journal={Pathophysiology : the official journal of the International Society for Pathophysiology},
  year={2007},
  volume={14 3-4},
  pages={135-46}
}
K-Cl cotransport is the coupled electroneutral movement of K and Cl ions carried out by at least four protein isoforms, KCC1-4. These transporters belong to the SLC12A family of coupled cotransporters and, due to their multiple functions, play an important role in the maintenance of cellular homeostasis. Significant information exists on the overall function of these transporters, but less is known about the role of the specific isoforms. Most functional studies were done on K-Cl cotransport… CONTINUE READING

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