K+ conductance modified by a titratable group accessible to protons from the intracellular side of the squid axon membrane.

@article{Wanke1979KCM,
  title={K+ conductance modified by a titratable group accessible to protons from the intracellular side of the squid axon membrane.},
  author={E. Wanke and E. Carbone and P. Testa},
  journal={Biophysical journal},
  year={1979},
  volume={26 2},
  pages={
          319-24
        }
}
  • E. Wanke, E. Carbone, P. Testa
  • Published 1979
  • Chemistry, Medicine
  • Biophysical journal
  • In the range of pH examined (5.2-10), variations of internal pH from high to low values result in a reversible decrease of the conductance of the open K channels, without significantly affecting the kinetics parameters. A linear plot of the conductance versus internal pH suggests the existence of a titratable group that has an apparent pKa of about 6.9, and that is accessible to protons only from the intracellular side of the membrane. 

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