K+ channel modulation of slow wave activity in the guinea-pig prostate.

@article{Nguyen2007KCM,
  title={K+ channel modulation of slow wave activity in the guinea-pig prostate.},
  author={D-T T Nguyen and Richard J. Lang and Betty Exintaris},
  journal={British journal of pharmacology},
  year={2007},
  volume={151 6},
  pages={
          828-36
        }
}
BACKGROUND AND PURPOSE The aim of this study was to investigate the role of different K(+) channel populations and the inhibitory effect of various exogenously applied K(+) channel openers in the regulation of slow wave activity in the guinea-pig prostate. EXPERIMENTAL APPROACH Recordings of membrane potential were made using intracellular microelectrodes. KEY RESULTS Tetraethylammonium (TEA 300 micro M and 1 mM), iberiotoxin (150 nM) and 4-aminopyridine (4-AP 1 mM) increased the frequency… CONTINUE READING
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