K+ Channels Expression in Hypertension After Arterial Injury, and Effect of Selective Kv1.3 Blockade with PAP-1 on Intimal Hyperplasia Formation

Abstract

K+ channels are central to vascular pathophysiology. Previous results demonstrated that phenotypic modulation associates with a change in Kv1.3 to Kv1.5 expression, and that Kv1.3 blockade inhibits proliferation of VSMCs cultures. To explore whether the Kv1.3 to Kv1.5 switch could be a marker of the increased risk of intimal hyperplasia in essential… (More)
DOI: 10.1007/s10557-014-6554-5

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@article{Cidad2014KCE, title={K+ Channels Expression in Hypertension After Arterial Injury, and Effect of Selective Kv1.3 Blockade with PAP-1 on Intimal Hyperplasia Formation}, author={Pino Cidad and Laura Novens{\'a} and Mar{\'i}a J. Garabito and Marc P. Batlle and Ana Paula Villela Dantas and Magdalena Heras and Jos{\'e} R L{\'o}pez-L{\'o}pez and Mar{\'i}a Teresa P{\'e}rez-Garc{\'i}a and Merc{\'e} Roqu{\'e}}, journal={Cardiovascular Drugs and Therapy}, year={2014}, volume={28}, pages={501-511} }