K(ATP) channel therapeutics at the bedside.

  title={K(ATP) channel therapeutics at the bedside.},
  author={Arshad Jahangir and Andre Terzic},
  journal={Journal of molecular and cellular cardiology},
  volume={39 1},
The family of potassium channel openers regroups drugs that share the property of activating adenosine triphosphate-sensitive potassium (K(ATP)) channels, metabolic sensors responsible for adjusting membrane potential-dependent functions to match cellular energetic demands. K(ATP) channels, widely represented in metabolically-active tissue, are heteromultimers composed of an inwardly rectifying potassium channel pore and a regulatory sulfonylurea receptor subunit, the site of action of… CONTINUE READING
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