Juvenile periodontitis as a model for neutrophil function: reduced binding of the complement chemotactic fragment, C5a.

@article{Dyke1983JuvenilePA,
  title={Juvenile periodontitis as a model for neutrophil function: reduced binding of the complement chemotactic fragment, C5a.},
  author={Thomas E Van Dyke and Michael J. Levine and Lawrence A. Tabak and Robert J. Genco},
  journal={Journal of dental research},
  year={1983},
  volume={62 8},
  pages={
          870-2
        }
}
The binding of the chemotactic complement fragment, C5a, to peripheral blood neutrophils of Localized Juvenile Periodontitis (LJP) patients and normal controls was quantitated using iodinated human C5a and a rapid centrifugation assay. There was a significant reduction in the number of binding sites per cell on neutrophils from the patient group, whereas the binding affinity remained the same as control values. 
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