Juvenile multiple sclerosis-like episodes associated with a defect of mitochondrial beta oxidation.

@article{Powell1990JuvenileMS,
  title={Juvenile multiple sclerosis-like episodes associated with a defect of mitochondrial beta oxidation.},
  author={Berkley R. Powell and Nancy G. Kennaway and William James Rhead and Clive Reece and Terry G. Burlingame and Neil R. M. Buist},
  journal={Neurology},
  year={1990},
  volume={40 3 Pt 1},
  pages={487-91}
}
We describe a young girl who presented with recurrent episodes of central nervous system (CNS) demyelination mimicking multiple sclerosis. Metabolic evaluations and decreased oxidation of [9,10(n)-3H] palmitate demonstrated defective mitochondrial beta oxidation, but complementation studies of the patient's cells, fused with cell lines with known defects of beta oxidation, failed to identify a known disorder. While progressive CNS demyelination has occurred in patients with defective… CONTINUE READING

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We describe a young girl who presented with recurrent episodes of central nervous system ( CNS ) demyelination mimicking multiple sclerosis .
We describe a young girl who presented with recurrent episodes of central nervous system ( CNS ) demyelination mimicking multiple sclerosis .
We describe a young girl who presented with recurrent episodes of central nervous system ( CNS ) demyelination mimicking multiple sclerosis .
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