Juvenile hormone and its receptor, methoprene-tolerant, control the dynamics of mosquito gene expression.

@article{Zou2013JuvenileHA,
  title={Juvenile hormone and its receptor, methoprene-tolerant, control the dynamics of mosquito gene expression.},
  author={Zhen Zou and Tusar Tirtha Saha and Sourav Saha Roy and Sang Woon Shin and Tyler W. H. Backman and Thomas Girke and Kevin P. White and Alexander S. Raikhel},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2013},
  volume={110 24},
  pages={
          E2173-81
        }
}
Juvenile hormone III (JH) plays a key role in regulating the reproduction of female mosquitoes. Microarray time-course analysis revealed dynamic changes in gene expression during posteclosion (PE) development in the fat body of female Aedes aegypti. Hierarchical clustering identified three major gene clusters: 1,843 early-PE (EPE) genes maximally expressed at 6 h PE, 457 mid-PE (MPE) genes at 24 h PE, and 1,815 late-PE (LPE) genes at 66 h PE. The RNAi microarray screen for the JH receptor… CONTINUE READING
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