JunB is a repressor of MMP-9 transcription in depolarized rat brain neurons.

@article{Rylski2009JunBIA,
  title={JunB is a repressor of MMP-9 transcription in depolarized rat brain neurons.},
  author={Marcin Rylski and Renata Amborska and Katarzyna Zybura and Piotr Michaluk and Beata Bielinska and Filip A. Konopacki and Grzegorz M. Wilczynski and Leszek Kaczmarek},
  journal={Molecular and cellular neurosciences},
  year={2009},
  volume={40 1},
  pages={98-110}
}
Matrix Metalloproteinase-9 (MMP-9) is an extracellularly operating enzyme involved in the synaptic plasticity, hippocampal-dependent long term memory and neurodegeneration. Previous studies have shown its upregulation following seizure-evoking stimuli. Herein, we show that in the rat brain, MMP-9 mRNA expression in response to pentylenetetrazole-evoked neuronal depolarization is transient. Furthermore, we demonstrate that in the rat hippocampus neuronal activation strongly induces JunB… CONTINUE READING

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