Jug r 6 is the allergenic vicilin present in walnut responsible for IgE cross-reactivities to other tree nuts and seeds

@inproceedings{Dubiela2018JugR6,
  title={Jug r 6 is the allergenic vicilin present in walnut responsible for IgE cross-reactivities to other tree nuts and seeds},
  author={Pawel Dubiela and Stefan Kabasser and Nicolas Smargiasso and S Geiselhart and Merima Bublin and Christine Hafner and Gabriel D Mazzucchelli and Karin Hoffmann-Sommergruber},
  booktitle={Scientific Reports},
  year={2018}
}
Walnuts are ranked high in the list of the culprit foods inducing severe allergic reactions. Jug r 2 has been identified as a major allergen in common walnut by cDNA cloning from a somatic cell line. So far, studies were performed on the allergenic activity of recombinant Jug r 2, yet there is still no evidence about the physicochemical characteristics of the natural allergen. Therefore, we aimed to purify and deeply characterize natural Jug r 2 and to assess IgE cross-reactivity among vicilins… CONTINUE READING
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