Judgement of the hypothalamic-pituitary-adrenocortical function in psychiatric patients by betamethasone-induced cortisol suppressibility

@article{Kasper1988JudgementOT,
  title={Judgement of the hypothalamic-pituitary-adrenocortical function in psychiatric patients by betamethasone-induced cortisol suppressibility},
  author={S. Kasper and Paul Vecsei and Peter Richter and Doris Haack and K. J. Diebold and L. Katzinski},
  journal={Journal of Neural Transmission},
  year={1988},
  volume={74},
  pages={161-174}
}
Betamethasone induced cortisol suppressibility was examined in 62 drug free consecutively admitted psychiatric inpatients. Betamethasone was choosen instead of the commonly used dexamethasone, because its double half-life compared to dexamethasone and its higher tissue availability. After a base-line evaluation with blood samples drawn at 8 a.m., 4 p.m., and 11 p.m., 0.5 mg or 1.0 mg betamethasone was given orally at 11 p.m. Postbetamethasone cortisol as well as betamethasone blood levels were… CONTINUE READING
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