Journey of TRAIL from Bench to Bedside and its Potential Role in Immuno-Oncology

Abstract

Induction of apoptosis in cancer cells has increasingly been the focus of many therapeutic approaches in oncology field. Since its identification as a TNF family member, TRAIL (TNF-related apoptosis-inducing ligand) paved a new path in apoptosis inducing cancer therapies. Its selective ability to activate extrinsic and intrinsic cell death pathways in… (More)
DOI: 10.4081/oncol.2017.332

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