Journaled string tree - a scalable data structure for analyzing thousands of similar genomes on your laptop

@article{Rahn2014JournaledST,
  title={Journaled string tree - a scalable data structure for analyzing thousands of similar genomes on your laptop},
  author={Ren{\'e} Rahn and David Weese and Knut Reinert},
  journal={Bioinformatics},
  year={2014},
  volume={30 24},
  pages={3499-505}
}
MOTIVATION Next-generation sequencing (NGS) has revolutionized biomedical research in the past decade and led to a continuous stream of developments in bioinformatics, addressing the need for fast and space-efficient solutions for analyzing NGS data. Often researchers need to analyze a set of genomic sequences that stem from closely related species or are indeed individuals of the same species. Hence, the analyzed sequences are similar. For analyses where local changes in the examined sequence… CONTINUE READING
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