Joint-preservation surgery for pediatric osteosarcoma of the knee joint

@article{Takeuchi2019JointpreservationSF,
  title={Joint-preservation surgery for pediatric osteosarcoma of the knee joint},
  author={Akihiko Takeuchi and Norio Yamamoto and Katsuhiro Hayashi and Hidenori Matsubara and Shinji Miwa and Kentaro Igarashi and Hiroyuki Tsuchiya},
  journal={Cancer and Metastasis Reviews},
  year={2019},
  volume={38},
  pages={709 - 722}
}
The multi-disciplinary approach involving imaging, multi-agent chemotherapy, meticulous surgical procedures, and careful postoperative care has facilitated an increase in the use of limb-sparing surgery for pediatric osteosarcoma. Osteosarcoma usually occurs around the metaphysis of the distal femur or proximal tibia and needs wide excision with the adjacent joint and replacement by a megaprosthesis. The recent advancement in imaging modalities and surgical techniques supports joint… 
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