Joint hypermobility syndrome

  title={Joint hypermobility syndrome},
  author={Juliette Ross and Rodney Grahame},
  journal={BMJ : British Medical Journal},
Joint hypermobility syndrome (JHS), previously known as benign joint hypermobility syndrome (BJHS), is a heritable disorder of connective tissue that comprises symptomatic hypermobility predisposing to arthralgia, soft tissue injury, and joint instability.1 It is indistinguishable from the hypermobility type of Ehlers-Danlos syndrome.2 Complications may include autonomic dysfunction, proprioceptive impairment, premature osteoarthritis, intestinal dysmotility, and laxity in other tissues causing… 

Joint hypermobility: emerging disease or illness behaviour?

Joint hypermobility syndrome is a common clinical entity which is much misunderstood, overlooked, misdiagnosed and mistreated and most authorities in the field find it clinically indistinguishable from the Ehlers-Danlos syndrome--hypermobility type (formerly, EDS type III).

The relationship between joint hypermobility and subacromial impingement syndrome and adhesive capsulitis of the shoulder

The results of this study indicated no significant difference between the SAIS group, the AC group, and the control group in terms of GJH and BJHS, which suggests that the probability of developing AC in those with JH may be lower.

Connective tissue, Ehlers–Danlos syndrome(s), and head and cervical pain

Assessment and management procedures are discussed in order to put some basis for ameliorating the actual patients' needs and nurturing future research.

Hypermobile Disorders and Their Effects on the Hip Joint

In this review, the recent literature evaluating the definitions, history, incidence, genetics, and histology of hypermobile disorders is investigated and the clinical evaluation, natural history, and resulting instability for patients presenting with a hypermobile hip are reviewed.

Two case presentations of profound labial edema as a presenting symptom of hypermobility-type Ehlers-Danlos syndrome.

The need for further research to determine incidence of labial edema in hypermobility-type EDS is highlighted and a potential correlation between profound laboratory edema and collagen disorders is elucidated.

A study exploring the prevalence of Joint Hypermobility Syndrome in patients attending a Musculoskeletal Triage Clinic

It is found that patients with JHS are likely toPresent with a greater number of painful joints and are more likely to present with wrist/hand pain as their main problem than those without JHS.

Living with joint hypermobility syndrome: patient experiences of diagnosis, referral and self-care

Timely diagnosis, raising awareness and access to health professionals who understand JHS may be particularly instrumental in helping to ameliorate symptoms and help patients to self-manage their condition.

Joint hypermobility syndrome subclassification in paediatrics: a factor analytic approach

The presenting signs and symptoms of children with JHS can be summarised in five clinically recognisable subtypes, which are associated with worse pain, fatigue, and reduced health-related quality of life.

Differential diagnosis and diagnostic flow chart of joint hypermobility syndrome/ehlers‐danlos syndrome hypermobility type compared to other heritable connective tissue disorders

The differential diagnosis of JHS/EDS‐HT is revised with those heritable connective tissue disorders which show a significant overlap with the former and mostly include EDS classic, vascular and kyphoscoliotic types, osteogenesis imperfecta, Marfan syndrome, Loeys–Dietz syndrome, arterial tortuosity syndrome, and lateral meningocele syndrome.



Joint hypermobility syndrome pain

  • R. Grahame
  • Medicine
    Current pain and headache reports
  • 2009
Over the past decade, it has become evident that of all the complications that may arise in JHS, chronic pain is arguably the most menacing and difficult to treat.

Joint hypermobility syndrome in childhood. A not so benign multisystem disorder?

JHS is poorly recognized in children with a long delay in the time to diagnosis, and although there is a referral bias towards joint symptoms, a surprisingly large proportion is associated with significant neuromuscular and motor development problems.

Hypermobility and the hypermobility syndrome.

Joint hypermobility in adults referred to rheumatology clinics.

The results show that joint hypermobility is common, familial, found in association with common rheumatic disorders, and statistically associated with osteoarthritis, and support the hypothesis that jointhypermobility predisposes to musculoskeletal disorders, especially osteOarthritis.

Amelioration of symptoms by enhancement of proprioception in patients with joint hypermobility syndrome.

Investigating whether a home-based exercise program could produce objective enhancement of proprioception as well as alleviate symptoms in JHS found appropriate exercises lead not only to symptomatic improvement, but also to demonstrable enhancement of objective parameters such as proprioceptions.

Diagnostic associations with hypermobility in rheumatology patients.

Clinique-based studies suggest an association between hypermobility and soft tissue rheumatic complaints and should be useful to the clinical rheumatologist.

Genitourinary Prolapse and Joint Hypermobility in Women

Epidemiology of general joint hypermobility and basis for the proposed criteria for benign joint hypermobility syndrome: review of the literature.

An analysis of criterion-referenced connections that identify similarities among major and minor clinical criteria that identify both GJH and benign joint hypermobility syndrome (BJHS) finds there is some evidence that arthralgia, the proposed BJHS major criterion, is a major component of allegedhypermobility-related problems.

Unexplained gastrointestinal symptoms and joint hypermobility: is connective tissue the missing link?

  • N. ZárateA. Farmer Q. Aziz
  • Medicine
    Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society
  • 2010
The prevalence of JHM or BJHS in patients with functional gastrointestinal disorders has not been examined and it is unclear whether these disorders are associated with each other or with other conditions.

Clinical study of hereditary disorders of connective tissues in a Chilean population: joint hypermobility syndrome and vascular Ehlers-Danlos syndrome.

JHS is very frequent but usually undiagnosed, and it is recommended that physicians learn to recognize the typical facial features of JHS and be able to identify blue sclera and that validated hypermobility criteria be routinely used.